There is no verified complete relic tier list here. Crypt Key is a known exploration option with a recorded chest-triggered health-and-mana recovery effect, while Family's Grace is a Midnight Edition defensive bonus that blocks an incoming attack and freezes nearby enemies while equipped, with a 60-second cooldown. Neither entry supports a universal best-in-slot verdict.
Compare the known options carefully
| Relic | What is established | What is not established here |
|---|---|---|
| Crypt Key | Has been shown fully restoring health and mana when a chest is opened | A verified full-release pickup route and final balance details |
| Family's Grace | Midnight Edition bonus; blocks an incoming attack and freezes nearby enemies, with a 60-second cooldown | Freeze duration, exact radius, boss exceptions, or a proven strength ranking |
The Crypt Key observation comes from pre-release play, so check the description in your own game before relying on it. It suggests an exploration use case around unopened chests; it does not establish that opening an empty room, revisiting a looted chest, or entering a boss arena triggers the same restoration.

Check the relic description in your version before relying on its effect.
Choose an effect for the current problem
Relics are equipment that can produce offensive or defensive effects. A useful selection starts with the obstacle: survival while exploring, repeated damage in an encounter, or support for your preferred weapon-and-Arcana style.
Read the trigger as carefully as the benefit. An effect tied to opening a chest is different from a passive bonus. If your immediate route has no usable chest, do not assume that particular trigger will help during it.
Family's Grace can provide a defensive margin when its effect is ready, but the 60-second cooldown prevents it from acting as permanent protection. Its premium-edition availability does not establish that it is stronger than exploration relics. Freeze duration and boss-specific behavior remain unconfirmed here.
Keep other games' relic lists separate
Items from Lament of Innocence do not become Belmont's Curse equipment simply because both games use the word relic. Black Bishop, White Bishop, and other names in an older game's catalog should not be inserted into this ranking without game-specific confirmation.
The same rule applies to their locations. An older entry's shop or dungeon route cannot establish how to obtain a Belmont's Curse relic.
Current recommendation
If you own Crypt Key and its in-game description matches the recorded recovery behavior, consider it for exploration where chest openings can make that effect useful. For other situations, compare the actual relic descriptions already in your inventory. The complete roster, final effect values, and a tested optimal combination remain unconfirmed here.
Compare Relic Locations: Known Items for the catalog limits and Family's Grace Relic for the dedicated edition-bonus guide.
